Subscribe
Call Us: 02380 97 07 33

Nicorandil (Ikorel): now second-line treatment for angina – risk of ulcer complications

Gov.UK

Updated advice on use of nicorandil as second-line treatment for stable angina – some ulcers may progress to complications unless treatment is stopped.

Advice for healthcare professionals:

  • Use nicorandil for treatment of stable angina only in patients whose angina is inadequately controlled by first line anti-anginal therapies, or who have a contraindication or intolerance to first line anti-anginal therapies such as beta-blockers or calcium antagonists
  • Nicorandil can cause serious skin, mucosal, and eye ulceration, including gastrointestinal ulcers which may progress to perforation, haemorrhage, fistula, or abscess
  • Stop nicorandil treatment if ulceration occurs—consider the need for alternative treatment or specialist advice if angina symptoms worsen
  • Please continue to report suspected adverse drug reactions to nicorandil or any other medicines on a Yellow Card

More information here

Leave a Reply

Disclaimer

The information on this site is provided 'as is' Whilst we stake our reputation on producing the most accurate information (and employ reasonable care and skill in providing this site's content), we cannot warrant that the information is accurate, complete and up to date. Neither can we guarantee uninterrupted performance and durability.
Click here to read our complete terms and conditions.