Clopidogrel and Proton Pump Inhibitors

We have just receive some indication from the manufacturers (Sanofi Aventis + Bristol-Myer Squibb ) that Clopidogrel-containing medicines and proton pump inhibitors (PPIs) ‘should be avoided unless absolutely necessary’. The preliminary studies indicate a cytochrome P450-type interaction. Clopidogrel is a pro-drug which is metabolised in the liver, partially by the cytochrome P450 complex. Hence any […]

Children’s OTC New Advice – bookapharmacist response

MHRA, the government agency which is responsible for ensuring that medicines and medical devices work, and are acceptably safe recently issued a new advice for children’s over the counter cough and cold medicine ( link ). The landmark finding is that these over the counter cough and cold medicine simply don’t work in children under […]

Important – Class 4 Alert

We have just been alerted to this packaging issue with Priadel 400mg Prolonged Release. The labelling on the rear panel of the cartons are wrong. On the side of the box where you place the dispensing label, you have Lithium Carbonate 200mg incorrectly printed on it. Please find more details on the MHRA site below: […]